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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3889 | Platycodin D | Prostaglandin Receptor , AMPK | |
Platycodin D may stimulate TNF-α synthesis or inhibit degradation of TNF-α mRNA. Platycodin D (10/30 μM) suppresses prostaglandin E2 production in rat peritoneal macrophages stimulated by the protein kinase C activator 1... | |||
T9779 | Protein kinase inhibitor 6 | ||
Protein kinase inhibitor 6 is a protein kinase inhibitor. | |||
TN1405 | Arnicolide D | Akt , Caspase , PI3K , STAT , mTOR | |
Arnicolide D is a sesquiterpene lactone. Arnicolide D isolates from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling path... | |||
T2458 | CID755673 | Serine/threonin kinase | |
CID755673 is an effective and specific cell-active inhibitor for PKD (IC50: 182 nM); exhibits selective PKD1 inhibition when compared with PLK1, AKT, CAMKIIα, CAK, and PKC isoforms. | |||
T2974 | Cyclovirobuxine D | CVB-D,Bebuxine,Cyclovirobuxin D | Apoptosis , Others , Akt , mTOR , Autophagy |
Cyclovirobuxine D (Bebuxine) is extracted from Buxus microphylla. | |||
T61163 | Protein kinase D inhibitor 1 | ||
Protein kinase D inhibitor 1 (compound 17m) is a potent pan-PKD inhibitor. It exhibits inhibitory activity in the low nanomolar range, with IC50 values ranging between 17 and 35 nM. By inhibiting protein kinase D, this c... | |||
T1863 | CID 2011756 | CID2011756,CID-2011756 | Serine/threonin kinase |
CID 2011756 is an ATP-competitive and specific PKD1 inhibitor. | |||
T2062 | Kb NB 142-70 | Serine/threonin kinase | |
kb NB 142-70 is a selective protein kinase D (PKD) inhibitor (IC50 values are 28.3, 58.7 and 53.2 nM for PKD1, 2 and 3 respectively). | |||
T5508 | PF-AKT400 | AKT protein kinase inhibitor | Akt |
PF-AKT400 (AKT protein kinase inhibitor) is a broadly selective and ATP-competitive inhibitor of Akt. | |||
T6440 | CGP 57380 | MNK1 Inhibitor | Apoptosis , MNK |
CGP 57380 (MNK1 Inhibitor) is a potent MNK1 inhibitor with IC50 of 2.2 μM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like kinases. | |||
T5891 | D-ERYTHRO-SPHINGOSINE | trans-4-Sphingenine,erythro-C18-Sphingosine,Erythrosphingosine | Phosphatase , Endogenous Metabolite , PKC |
D-erythro-Sphingosine (trans-4-Sphingenine) is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator | |||
T2492 | Perifosine | NSC 639966,D21266,KRX-0401 | Apoptosis , Akt , Autophagy |
Perifosine (KRX-0401) is an oral-active, alkyl-phosphocholine Akt inhibitor with potential antineoplastic activity. | |||
TN1499 | Cimiracemoside C | Cimicifugoside M | AMPK |
Cimiracemoside C (Cimicifugoside M) is an active component of Cimicifuga racemosa. It activates AMPK and has the potential activity against diabetes. | |||
TQ0104 | CRT0066101 dihydrochloride | Serine/threonin kinase | |
CRT0066101 dihydrochloride is an effective and selective PKD inhibitor (IC50s: 1, 2.5 and 2 nM for PKD1, 2, and 3). | |||
T13017 | STL127705 | Compound L,7-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-3-(3-fluorophenyl)pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione | DNA-PK , Others |
STL127705 (Compound L) is a potent Ku 70/80 heterodimer protein inhibitor and inhibits Ku70/80-DNA interaction with IC50 of 3.5 μM. STL127705 inhibits the activation of Ku-dependent DNA-PKCS kinase with IC50 of 2.5 μM. | |||
T19500 | Palmitelaidic Acid | trans-Palmitoleic acid,9-trans-Hexadecenoic acid | Glucokinase , AMPK , PPAR |
Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue. | |||
T9256 | N-Cyclohexyl-4-[1-(1-piperazinyl)-2,6-naphthyridin-3-yl]-2-pyridinamine | Serine/threonin kinase , PKC | |
N-Cyclohexyl-4-[1-(1-piperazinyl)-2,6-naphthyridin-3-yl]-2-pyridinamine is a novel 2,6-naphthyridine identified by high throughput screen (HTS) as a dual protein kinase C/D (PKC/PKD) inhibitor[1]. | |||
T4511 | ST271 | ST 271 | Phospholipase , Tyrosine Kinases |
ST271 is an effective protein tyrosine kinase (PTK) inhibitor. | |||
T6904 | Necrosulfonamide | (E)-Necrosulfonamide | MLK |
(E)-Necrosulfonamide ((E)-Necrosulfonamide) is an inhibitor of necroptosis. Blocks mixed lineage kinase domain-like protein (MLKL), a critical substrate of receptor-interacting serine-threonine kinase 3 (RIP3) during nec... | |||
T77504 | JAK1/2/3 Inhibitor 1 | PKA | |
JAK1/2/3 Inhibitor 1 is a potent protein kinase inhibitor.JAK1/2/3 Inhibitor 1 has antitumor activity that inhibits the growth of a variety of cancer cell lines. It inhibits the growth of cancer cells by binding to the c... |